Welcome to the Merkel lab!

The Merkel lab is based in the Department of Pharmacy at LMU Munich and focuses on rational design of novel non-viral and targeted nanosized RNA delivery systems. We are especially interested in local drug, gene, mRNA, and siRNA delivery with an emphasis on pulmonary delivery for applications in cancer immunology, inflammatory diseases, and respiratory viruses. We apply DoE, MD simulation, and machine learning algorithms in our computational approaches and combine them with experimental organic synthesis and biophysical work as well as in vitro  and in vivo validation. 

Picture: Susanne Petzel