Anny Nguyen

anny.nguyen@cup.

Since October 2022 PhD Student, Merkel Lab LMU Munich
2022 Research Intern, Chiba University, Japan
2022 Short Term Intern, University of Hawaiʻi at Hilo
2021 Board License as Pharmacist
2021 Pharmacy Resident, Sanofi-Aventis, Berlin
2020 Pharmacy Resident, Retail Pharmacy, Munich
2015 - 2020 Pharmacy School, Ludwig-Maximilians-Universität München, Germany

Felix Sieber-Schäfer, Adrian P. E. Kromer, Muge Molbay, Simone Pinto Carneiro, Min Jiang, Anny Nguyen, Joschka T. Müller, Johan Farfan Benito, Olivia M. Merkel: Machine-Learning-Guided Exploration of a Small Orthogonal PBAE Polymer Library for In Vitro siRNA Delivery Optimization
ACS Nano Med. (2026) https://doi.org/10.1021/acsnanomed.6c00078

Min Jiang, Dana Matzek, Anny Nguyen, Bastian Popper, Olivia M. Merkel: Protocol for co-culture of murine bone marrow-derived dendritic cells with OT-I mouse CD8+ T cells to evaluate immune activation efficacy
Protocol 2026, Volume 7, Issue 2104621; https://doi.org/10.1016/j.xpro.2026.104621

Sophie Thalmayr, Joschka Müller, Vivien Polewka, Irene Gialdini, Anny Nguyen, Christian Dohmen, Don C. Lamb, Olivia M. Merkel and Ernst Wagner: mRNA Delivery by Lipoamino Fatty Acid–Peptide Polyplexes in Different Lung Cell Models and Lungs
Polymers 2026, 18(11), 1368; https://doi.org/10.3390/polym18111368

Min Jiang, Felix Sieber-Schäfer, Simone P Carneiro, Dana Matzek, Anny Nguyen, Diana Leidy Porras-Gonzalez, Arun Kumar Verma, Miriam Kolog-Gulko, David C Jürgens, Gerald Burgstaller, Bastian Popper, Xun Sun, Olivia M Merkel*:  A hybrid polymeric system for pulmonary mRNA delivery: Advancing mucosal vaccine development.
Cell Biomaterials. 2026; 100311. DOI: 10.1016/j.celbio.2025.100311 

L. Ouologuem, A. Kübler, S. Ouologuem, A. Hadzic, J. B. Stöckl, A. C. Siciliano, S. Forciniti, S. Nigro, H. Iuele, V. Onesto, A. Nguyen, D. Matzek, C. Abrahamian, C. Grimm, B. Popper, G. Gigli, L. L. del Mercato, O. M. Merkel, T. Frohlich, S. T. and K. Bartel,  Loss of Two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC, 
Front. Immunol.; doi: 10.3389/fimmu.2025.1668066 (2025)

Müller, J.T., Caruso, S., Nguyen, A., Jürgens, D.,C., Kromer, A.P.E., Sheshachala, S., Adams, N.B.P., Merkel, O.M. Development of Trastuzumab-coupled, siRNA encapsulating mPolyplexes targeting HER2 overexpressing cancer cells. European Journal of Pharmaceutics and Biopharmaceutics, Volume 217, 2025, 114904, ISSN 0939-6411, https://doi.org/10.1016/j.ejpb.2025.114904.

F. Sieber-Schäfer, M. Jiang, A. Kromer, A. Nguyen, M. Molbay, S. Pinto Carneiro, D. Jürgens, G. Burgstaller, B. Popper, B. Winkeljann, O. M. Merkel, Machine Learning-Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery. Adv. Funct. Mater. 2025, e02805.

Siyu Chen*, Anny Nguyen*, Joschka T Müller, Müge Molbay, Aditi Mehta, Sahana Sheshachala, Kemal Baskaya, Nathan Adams, Simone P Carneiro, Olivia M Merkel*: Engineered-affibody conjugates contribute to the specific targeting and cellular retention of polyplexes in Erbb3 overexpressed lung cancer cells Eur J Pharm Sci 2025

David C. Jürgens, Joschka T. Müller, Anny Nguyen, Olivia M Merkel*: Tailoring lipid nanoparticles for T-cell targeting in allergic asthma: Insights into efficacy and specificity.
European Journal of Pharmaceutics and Biopharmaceutics 2024, doi:10.1016/j.ejpb.2024.114242