Dr. Simone Carneiro

Dr. Simone Pinto Carneiro (Postdoc)

Since July 2024 Group Leader, LMU Munich
July 2022- June 2024 Humboldt-Fellow, LMU Munich
2021-2022 Postdoc, LMU Munich
2019-2021: Postdoc, Universidade Federal de Ouro Preto (UFOP), Ouro Preto-MG, Brazil
2017-2018: Visiting PhD Student, Institut Galien Paris-Sud, Université Paris-Sud, Paris, France
2014-2018: PhD in Biotechnology, Universidade Federal de Ouro Preto (UFOP), Ouro Preto-MG, Brazil
2012-2012: Master Intern, Université Lille 2, Lille, France
2011-2013: M.Sc. in Pharmaceutical Sciences, Universidade Federal de Ouro Preto (UFOP), Ouro Preto-MG, Brazil
2005-2010: Degree in Pharmacy, Universidade Federal de Ouro Preto (UFOP), Ouro Preto-MG, Brazil

S. Rademacker, S. Carneiro, M. Molbay, F. Catapano, I. Forné, A. Imhof, R. Wibel, C. Heidecke, P. Hölig, O. Merkel, The impact of lipid compositions on siRNA and mRNA lipid nanoparticle performance for pulmonary delivery, European Journal of Pharmaceutical Sciences, 2025, 107182, ISSN 0928-0987

F. Sieber-Schäfer, M. Jiang, A. Kromer, A. Nguyen, M. Molbay, S. Pinto Carneiro, D. Jürgens, G. Burgstaller, B. Popper, B. Winkeljann, O. M. Merkel, Machine Learning-Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery. Adv. Funct. Mater. 2025, e02805.

Siyu Chen, Anny Nguyen, Joschka T Müller, Müge Molbay, Aditi Mehta, Sahana Sheshachala, Kemal Baskaya, Nathan Adams, Simone P Carneiro, Olivia M Merkel*: Engineered-affibody conjugates contribute to the specific targeting and cellular retention of polyplexes in Erbb3 overexpressed lung cancer cells Eur J Pharm Sci 2025

Siyu Chen, Mariem Triki, Simone P Carneiro, Olivia M Merkel*: A Novel Micelleplex for Tumour-Targeted Delivery of CRISPR-Cas9 against KRAS-Mutated Lung Cancer
Nanoscale, 2025, DOI: 10.1039/D4NR03471F.

Marta Cabibbo, Cinzia Scialabba, Emanuela F Craparo E, Simone P Carneiro, Olivia M Merkel, Gennara Cavallaro: Diving into RNAi Therapy: An Inhalable Formulation Based on Lipid-Polymer Hybrid Systems for Pulmonary Delivery of siRNA
Biomacromolecules 2024: DOI: 10.1021/acs.biomac.4c00387

Siyu Chen, Simone P Carneiro, Olivia M Merkel: Anionic polymer coating for enhanced delivery of Cas9 mRNA and sgRNA nanoplexes
Biomaterials Science 2024: https://pubs.rsc.org/en/content/articlelanding/2025/bm/d4bm01290a

Carneiro, SP, Müller, JT, Merkel, OM: Fluorescent Techniques for RNA Detection in Nanoparticles. Methods in Molecular Biology, vol 2822. 2024. https://doi.org/10.1007/978-1-0716-3918-4_14

Carneiro S, Müller JT, Merkel OM. Targeted Molecular Therapeutics for Pulmonary Diseases: Addressing the Need for Precise Drug Delivery. Handb Exp Pharmacol. 2024 Jan 5. doi: 10.1007/164_2023_703.

Hartl N, Jürgens DC, Carneiro S, König AC, Xiao X, Liu R, Hauck SM, Merkel OM. Protein corona investigations of polyplexes with varying hydrophobicity - From method development to in vitro studies. Int J Pharm. 2023 Aug 25;643:123257. doi: 10.1016/j.ijpharm.2023.123257.

Carneiro SP, Greco A, Chiesa E, Genta I, Merkel OM. Shaping the future from the small scale: dry powder inhalation of CRISPR-Cas9 lipid nanoparticles for the treatment of lung diseases. Expert Opin Drug Deliv. 2023 Mar 12:1-17. doi: 10.1080/17425247.2023.21852

SANTOS, O.D.H., PERASOLI, F.B., SILVA, L.S.B., FIGUEIREDO, B.I.C., BASTOS, J.C.S.A., CARNEIRO, S.P., TEIXEIRA, L. F. M. Single step process for preparation of nanocomposites constituted of poly(methyl methacrylate-co-dimethylacrylamide) with silver nanoparticles and general uses, Filling number: BR 10 2020 0129830

SANTOS, O.D.H., ANDRADE, M.H.G., CARVALHO, K.V., CARNEIRO, S.P. Method for development of rifampicin lipid nanoparticles entrapped in microparticles, Filling number: BR 10 2017 015666 4

SANTOS, O.D.H., CARNEIRO, S.P., JERONIMO, V.T., AGUIAR, T.A. Production of nanometric systems – clobetasol propionate nanoemulsions and polymeric nanocapsules associated to vegetal oils for topical use in dermatitis treatment, Filling number: BR 10 2013 010417 5