Dr. Simone Carneiro
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Dr. Simone Pinto Carneiro (Postdoc)
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Since July 2024 Group Leader, LMU Munich |
| Publications: |
S. Rademacker, S. Carneiro, M. Molbay, F. Catapano, I. Forné, A. Imhof, R. Wibel, C. Heidecke, P. Hölig, O. Merkel, The impact of lipid compositions on siRNA and mRNA lipid nanoparticle performance for pulmonary delivery, European Journal of Pharmaceutical Sciences, 2025, 107182, ISSN 0928-0987 F. Sieber-Schäfer, M. Jiang, A. Kromer, A. Nguyen, M. Molbay, S. Pinto Carneiro, D. Jürgens, G. Burgstaller, B. Popper, B. Winkeljann, O. M. Merkel, Machine Learning-Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery. Adv. Funct. Mater. 2025, e02805. Siyu Chen, Anny Nguyen, Joschka T Müller, Müge Molbay, Aditi Mehta, Sahana Sheshachala, Kemal Baskaya, Nathan Adams, Simone P Carneiro, Olivia M Merkel*: Engineered-affibody conjugates contribute to the specific targeting and cellular retention of polyplexes in Erbb3 overexpressed lung cancer cells Eur J Pharm Sci 2025 Siyu Chen, Mariem Triki, Simone P Carneiro, Olivia M Merkel*: A Novel Micelleplex for Tumour-Targeted Delivery of CRISPR-Cas9 against KRAS-Mutated Lung Cancer Marta Cabibbo, Cinzia Scialabba, Emanuela F Craparo E, Simone P Carneiro, Olivia M Merkel, Gennara Cavallaro: Diving into RNAi Therapy: An Inhalable Formulation Based on Lipid-Polymer Hybrid Systems for Pulmonary Delivery of siRNA Siyu Chen, Simone P Carneiro, Olivia M Merkel: Anionic polymer coating for enhanced delivery of Cas9 mRNA and sgRNA nanoplexes Carneiro, SP, Müller, JT, Merkel, OM: Fluorescent Techniques for RNA Detection in Nanoparticles. Methods in Molecular Biology, vol 2822. 2024. https://doi.org/10.1007/978-1-0716-3918-4_14 Carneiro S, Müller JT, Merkel OM. Targeted Molecular Therapeutics for Pulmonary Diseases: Addressing the Need for Precise Drug Delivery. Handb Exp Pharmacol. 2024 Jan 5. doi: 10.1007/164_2023_703. Hartl N, Jürgens DC, Carneiro S, König AC, Xiao X, Liu R, Hauck SM, Merkel OM. Protein corona investigations of polyplexes with varying hydrophobicity - From method development to in vitro studies. Int J Pharm. 2023 Aug 25;643:123257. doi: 10.1016/j.ijpharm.2023.123257. Carneiro SP, Greco A, Chiesa E, Genta I, Merkel OM. Shaping the future from the small scale: dry powder inhalation of CRISPR-Cas9 lipid nanoparticles for the treatment of lung diseases. Expert Opin Drug Deliv. 2023 Mar 12:1-17. doi: 10.1080/17425247.2023.21852 Registre C, Soares RDOA, Rubio KTS, Santos ODH, Carneiro SP. A Systematic Review of Drug-Carrying Nanosystems Used in the Treatment of Leishmaniasis. ACS Infect Dis. 2023 Mar 10;9(3):423-449. doi: 10.1021/acsinfecdis.2c00632. PINTO CARNEIRO, SIMONE; MOINE, LAURENCE; TESSIER, BARBARA; NICOLAS, VALERIE; DOS SANTOS, ORLANDO; FATTAL, ELIAS. Pyrazinoic acid-Poly(malic acid) biodegradable nanoconjugate for efficient intracellular delivery. Precision Nanomedicine, v. 2, p. 303-317, 2019. DOI: 10.33218/prnano2(3).190523.1 CARNEIRO SP, CARVALHO KV, DE OLIVEIRA AGUIAR SOARES RD, CARNEIRO CM, DE ANDRADE MHG, DUARTE RS, DOS SANTOS ODH. Functionalized rifampicin-loaded nanostructured lipid carriers enhance macrophages uptake and antimycobacterial activity. Colloids and Surfaces B: Biointerfaces. v. 175, p. 306-313, 2019. DOI: 10.1016/j.colsurfb.2018.12.003 SEIBERT J.B., RODRIGUES I.V., CARNEIRO S.P., AMPARO T.R., LANZA J.S., FRÉZARD F.J.G., SOUZA G.H.B., SANTOS O.D.H. Seasonality study of essential oil from leaves of Cymbopogon densiflorus and nanoemulsion development with antioxidant activity. Flavour and Fragrance Journal. v.00, p.1–10, 2018. DOI:10.1002/ffj.3472 HOANG THI, T.H., LHAFIDI, S., CARNEIRO, S.P., FLAMENT, M.-P. Feasability of a new process to produce fast disintegrating pellets as novel multiparticulate dosage form for pediatric use. International Journal of Pharmaceutics, v. 496, p. 842-849, 2015. DOI: 10.1016/j.ijpharm.2015.09.049 SIMONE PINTO CARNEIRO, RICARDO MACHADO CRUZ, ORLANDO DAVID HENRIQUE DOS SANTOS. Evaluation of short cycles of ultrasound application in nanoemulsions to obtain nanocapsules. Ultrasonics Sonochemistry, v. 27, p. 536–542, 2015. DOI: 10.1016/j.ultsonch.2015.04.002 IVANILDES V. RODRIGUES, JANAINA B. SEIBERT, SIMONE P. CARNEIRO, GUSTAVO H.B. DE SOUZA, ORLANDO D.H. DOS SANTOS AND NORBERTO P. LOPES. Preparation and in vitro Evaluation of α and β-Amyrins Loaded Nanoemulsions. Current Pharmaceutical Biotechnology (Print), v. 14, p. 1235-1241, 2013. DOI: 10.2174/1389201015666140317121647 |
| Patents: |
SANTOS, O.D.H., PERASOLI, F.B., SILVA, L.S.B., FIGUEIREDO, B.I.C., BASTOS, J.C.S.A., CARNEIRO, S.P., TEIXEIRA, L. F. M. Single step process for preparation of nanocomposites constituted of poly(methyl methacrylate-co-dimethylacrylamide) with silver nanoparticles and general uses, Filling number: BR 10 2020 0129830 SANTOS, O.D.H., ANDRADE, M.H.G., CARVALHO, K.V., CARNEIRO, S.P. Method for development of rifampicin lipid nanoparticles entrapped in microparticles, Filling number: BR 10 2017 015666 4 SANTOS, O.D.H., CARNEIRO, S.P., JERONIMO, V.T., AGUIAR, T.A. Production of nanometric systems – clobetasol propionate nanoemulsions and polymeric nanocapsules associated to vegetal oils for topical use in dermatitis treatment, Filling number: BR 10 2013 010417 5 |
