Dr. Joschka Müller
| Dr. Joschka Müller (Postdoc)
|
Since Jan 2026 Postdoc, Merkel Lab LMU Munich |
| Publications: |
Felix Sieber-Schäfer, Adrian P. E. Kromer, Muge Molbay, Simone Pinto Carneiro, Min Jiang, Anny Nguyen, Joschka T. Müller, Johan Farfan Benito, Olivia M. Merkel: Machine-Learning-Guided Exploration of a Small Orthogonal PBAE Polymer Library for In Vitro siRNA Delivery Optimization Sophie Thalmayr, Joschka Müller, Vivien Polewka, Irene Gialdini, Anny Nguyen, Christian Dohmen, Don C. Lamb, Olivia M. Merkel and Ernst Wagner: mRNA Delivery by Lipoamino Fatty Acid–Peptide Polyplexes in Different Lung Cell Models and Lungs Felix Sieber-Schäfer, Adrian P E Kromer, Müge Molbay, Simone P Carneiro, Min Jiang, Anny Nguyen, Joschka T Müller, Johan F Benito, Olivia M Merkel: Machine-Learning-Guided Exploration of a Small Orthogonal PBAE Polymer Library for In Vitro siRNA Delivery Optimization. Müller, J.T., Caruso, S., Nguyen, A., Jürgens, D.,C., Kromer, A.P.E., Sheshachala, S., Adams, N.B.P., Merkel, O.M. Development of Trastuzumab-coupled, siRNA encapsulating mPolyplexes targeting HER2 overexpressing cancer cells. European Journal of Pharmaceutics and Biopharmaceutics, Volume 217, 2025, 114904, ISSN 0939-6411, https://doi.org/10.1016/j.ejpb.2025.114904. Rademacker, S., Müller, J.T., Kromer, A.P.E., Carneiro, S.P., Merkel, O.M. Nanoparticle-Mediated siRNA Delivery in Human Epithelial Lung Cells Cultured at the Air–Liquid Interface. In: Sioud, M. (eds) RNA Therapeutics. Methods in Molecular Biology, vol 2965. Humana, New York, NY. 2025 https://doi.org/10.1007/978-1-0716-4742-4_21 Siyu Chen, Anny Nguyen, Joschka T Müller, Müge Molbay, Aditi Mehta, Sahana Sheshachala, Kemal Baskaya, Nathan Adams, Simone P Carneiro, Olivia M Merkel*: Engineered-affibody conjugates contribute to the specific targeting and cellular retention of polyplexes in Erbb3 overexpressed lung cancer cells Eur J Pharm Sci 2025 Müller, JT, Kromer, APE, Ezaddoustdar, A, Alexopoulos, I, Steinegger, KM, Porras-Gonzalez, DL, Berninghausen, O, Beckmann, R, Braubach, P, Burgstaller, G, Wygrecka, M, and Merkel, OM*: Nebulization of RNA-Loaded Micelle-Embedded Polyplexes as a Potential Treatment of Idiopathic Pulmonary Fibrosis ACS Applied Materials & Interfaces DOI: 10.1021/acsami.4c21657 Carneiro, SP, Müller, JT, Merkel, OM: Fluorescent Techniques for RNA Detection in Nanoparticles. Methods in Molecular Biology, vol 2822. 2024. https://doi.org/10.1007/978-1-0716-3918-4_14 Jin Y, Wang X, Kromer APE, Müller J, Zimmermann C, Xu Z, Hartschuh A, Adams F, Merkel OM: Role of Hydrophobic Modification in Spermine-Based Poly(β-amino ester)s for siRNA Delivery and Their Spray-Dried Powders for Inhalation and Improved Storage Biomacromolecules 2024, ahead of print, doi: 10.1021/acs.biomac.4c00283 David C. Jürgens, Joschka T. Müller, Anny Nguyen, Olivia M Merkel*: Tailoring lipid nanoparticles for T-cell targeting in allergic asthma: Insights into efficacy and specificity. Simone Carneiro, Joschka T Müller , Olivia M Merkel: Targeted Molecular Therapeutics for Pulmonary Diseases: Addressing the Need for Precise Drug Delivery. Rima Kandil, Domizia Baldassi, Sebastian Böhlen, Joschka T Müller, David C Jürgens, Tonia Bargmann, Susann Dehmel, Yuran Xie, Aditi Mehra, Olivia M Merkel*: GATA3 knockdown in activated T cells via pulmonary siRNA delivery as novel therapy for allergic asthma. |
